Imikhiqizo
Isebenza ngokukhethekile ekukhiqizeni utshwala be-propargyl, i-1,4 butynediol kanye ne-3-chloropropyne
Ukukhiqizwa kwe-1, 4-butanediol (BDO) ngendlela ye-maleic anhydride
Inqubo ye-esterification kanye ne-hydrogenation ye-maleic anhydride yathuthukiswa yi-Davy Mckee Company e-United Kingdom.Iqukethe izinyathelo ezintathu: (1) ukusabela phakathi kwe-maleic anhydride ne-ethanol;② I-BDO yalungiswa nge-hydrolysis ye-diethyl maleic acid;③ Ukuhlukaniswa nokucwengwa kwemikhiqizo yokusabela.Isilinganiso se-BDO, GBL ne-THF singashintshwa ngokulungisa izimo zenqubo.Ngenxa yenzuzo yezindleko zokukhiqizwa kwe-BDO, amathuluzi amaningi amasha akhiwe yile nqubo eminyakeni yamuva, futhi okuwumkhuba oyinhloko wokuthuthukiswa kwenqubo yokukhiqiza ye-BDO.Impendulo esuka ku Esterification:
Ukusabela kwe-Hydrogenation
Njengamanje, kukhona nezinqubo ze-n-butane-maleic anhydride, eziqala ukucutshungulwa yi-oxidation yesigaba segesi se-n-butane ukuze kukhiqizwe i-anhydride ye-maleic, bese i-anhydride yesilisa ifakwa esterfied nge-methanol ukukhiqiza i-dimethyl maleate.Ukuguqulwa kwe-anhydride yesilisa kungafinyelela ku-100% ngaphansi kwe-catalyst efanele.Ekugcineni, i-BDO ikhiqizwa yi-hydrogenation kanye ne-hydrolysis ye-maleic anhydride catalyst.Izinzuzo zale nqubo ukuthi kulula ukuhlukanisa ukungcola okufana ne-methanol namanzi ngemva kokufakwa kwe-esterification, futhi izindleko zokuhlukanisa ziphansi.Ngaphezu kwalokho, ukuntengantenga kwe-dimethyl maleate kuyanda, okwenza ububanzi bokusebenza kwesigaba segesi se-hydrogenation banzi, futhi izinga lokuguqulwa kwe-methanol esterification lingaphezu kwama-99.7%.Ngakho-ke, ayikho inkinga yokuqala yokuhlanza i-diethyl maleate.Ngakho-ke, akudingekile ukuphinda kusetshenziswe kabusha yonke i-anhydride ye-maleic engaphenduliwe kanye ne-mono-methyl ester, kodwa i-methanol ehlanzekile kuphela, eyenza inqubo yokukhiqiza ibe lula futhi inciphise kakhulu ukutshalwa kwezimali okuphelele kwephrojekthi uma kuqhathaniswa nobuchwepheshe bangaphambilini.
